PROFESSOR ALUMNI GRADUATES UNDERGRADUATES

yshim@konkuk.ac.kr
Phone : 02-450-4059
Fax : 02-455-9956

PROFESSOR: Yhong-Hee Shim, Ph.D.

·B. Sc. Seoul National University

·M. Sc. University of Western Ontario, Canada

Thesis Title:

The purification and properties of monoacylglycerol kinase from bovine brain

Supervisor :

K. P. Strickland, Ph. D.

·Ph. D. Indiana University, Bloominton, IN, USA

Thesis Title:

Functional analysis of the Caenorhabditis elegans transcription factor,ELT-1, in yeast

Supervisor :

Tom Blumenthal, Ph. D.

·Postdoctoral fellow, Indiana University, Bloomington, IN, USA

Supervisor :

Susan Strome, Ph. D.


PUBLICATIONS

Min H, Youn E, Shim YH. Maternal caffeine intake disrupts eggshell integrity and retards larval development by reducing yolk production in a Caenorhabditis elegans model. Nutrients 12(5), 1334 (2020).

Min H, Kim JS, Ahn J, Shim YH. Gliadin intake causes disruption of the intestinal barrier and an increase in germ cell apoptosis in a Caenorhabditis elegans model. Nutrients 11(11), 2587 (2019).

Min HM, Lee YU, Shim YH, Kawasaki I. Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans. PLos Genet. 15(5):e1008150 (2019).

Lim SD, Min H, Youn E, Kawasaki I, Shim YH. Gliadin intake induces oxidative-stress responses in Caenorhabditis elegans. Biochem Biophys Res Commun. 503(3):2139-2145 (2018).

Yoon S, Kawasaki I, Shim YH. cyb-1, a C. elegans B-type cyclin, maintains proper position and number of centrosomes during spermatogenesis. J Cell Sci. 130 (16): 2722-2735 (2017).

Min H, Sung M, Son M, Kawasaki I, Shim YH. Transgenerational effects of proton beam irradiation on Caenorhabditis elegans germline apoptosis. Biochem Biophys Res Commun 490 (3):608-615 (2017).

Sung M, Kawasaki I, Shim YH. Depletion of cdc-25.3, a Caenorhabditis elegans orthologue of cdc25, increase physiological germline apoptosis. FEBS Lett 591 (14):2131-2146 (2017).

Oh S, Yoon S, Youn E, Kawasaki I, Shim YH. cdc-25.2, a Caenorhabditis elegans ortholog of cdc25, is required for male tail morphogenesis. Biochem Biophys Res Commun 482 (4):1213-1218 (2017).

Son M, Kawasaki I, Oh BK, Shim YH. LIN-23, an E3 ubiquitin ligase component, is requird for the repression of CDC-25.2 activity during intestinal development in Caenorhabditis elegans. Mol Cells 39(11):834-840 (2016).

Oh S, Kawasaki I, Park JH, Shim YH. cdc-25.4, a Caenorhabditis elegans ortholog of cdc25, is required for male mating behavor. G3 (Bethesda) 6(12):4127-4138 (2016).

Min H, Youn E, Kawasaki I, Shim YH. Caffeine-induced food-avoidance behavior is mediated by neuroendocrine signals in Caenorhabditis elegans. BMB Rep 50(1):31-36 (2017).

Al-Amin M, Min H, Shim YH, Kawasaki I. Somatically expressed germ-granule components, PGL-1 and PGL-3, repress programmed cell death in C. elegans. Sci Rep. Sep 21;6:33884 (2016). Lee YU, Son M, Kim J, Shim YH, Kawasaki I. CDC-25.2, a C. elegans ortholog of cdc25, is essential for the progression of intestinal division. Cell Cycle 15(5):654-666 (2016).

Al-Amin M, Kawasaki I, Gong J, Shim YH. Caffeine induces the stress response and up-regulates heat shock proteins in Caenorhabditis elegans. Mol Cells 39 (2): 163-168 (2016).

Min H, Shim YH, Kawasaki I. Loss of PGL-1 and PGL-3, a family of constitutive P-granule components, prevent excessive levels of germline apoptosis in Caenorhabditis elegans. J Cell Sci 129:341-353 (2016).

Ponnarath K, Choi JS, Bae J, Shim YH, Oh BK. Increased stability of nucleolar PinX1 in the presence of TERT. Mol Cells 38(9):814-820 (2015).

Min H, Kawasaki I, Gong JM, Shim YH. Caffeine induces high expression of cyp-35A family genes and inhibits the early larval development in Caenorhabditis elegans. Mol Cells 38(3): 236-242 (2015).

Ko S, Kawasaki I, Shim YH. PAB-1, a Caenorhabditis elegans poly(A)-binding protein, regulates mRNA metabolism in germline by interacting with CGH-1 and CAR-1. PLOS ONE 8:e84798 (2013).

Kawasaki I, Jeong MH, Yun YJ, Shin YK, Shim YH. Cholesterol-responsive metabolic proteins are required for larval development in Caenorhabditis elegans. Mol Cells 36:410-416 (2013).

Yoon SH, Kawasaki I, Shim YH. CDC-25.1 controls the rate of germline mitotic cell cycle by counteracting WEE-1.3 and by positively regulating CDK-1 in Caenorhabditis elegans. Cell Cycle 11:1354-1363 (2012).

Kawasaki I, Jeong MH, Shim YH. Regulation of sperm-specific proteins by IFE-1, a germline-specific homolog of eIF4E, in C. elegans. Mol Cells 31:191-197 (2011).

Kawasaki I, Jeong MH, Oh BK, Shim YH. Apegenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation. FEBS Lett 584:3587-3591 (2010).

Jeong MH, Kawasaki I, and Shim YH. A circulatory transcriptional regulation among daf-9, daf-12, and daf-16 mediates larval development upon cholesterol starvation in Caenorhabditis elegans. Dev Dyn 239:1931-1940 (2010).

Kim J, Kawasaki I, and Shim YH. cdc-25.2, a C. elegans ortholog of cdc25, is required to promote oocyte maturation. J Cell Sci 123:993-1000 (2010).

Ko S, Lee AR, Kim E, Kim J, Kawasaki I, and Shim YH. Two mutations in pab-1 encoding poly(A)-binding protein show similar defects in germline stem cell proliferation but different logevity in C. elegans. Mol Cells 30:167-172 (2010).

Shim YH, Chun JH, Lee EY, and Paik YK. Role of cholesterol in germ-line development of Caenorhabditis elegans. Mol Rep Dev 61:358-366 (2002).

Shim YH, Byun EK, Lee MJ, Huh J, and Kim CW. Anti-apoptotic role of bfl-1 in staurosporine-treated B-lymphoblastic cells. International J Hematology 72:484-490 (2000).

Shim YH, Kang GH, and Ro JY. Correlation of p16 hypermethylation with the p16 protein loss in sporadic gastric carcinomas. Lab Invest 80:689-695 (2000).

Shim YH. elt-1, a gene encoding a Caenorhabditis elegans GATA transcription factor, is highly expressed in the germ lines with msp genes as the potential targets Mol Cells 9: 535-541 (1999).

Kawasaki I, Shim YH, Kirchner J, Kaminker J, Wood B, and Strome S. PGL-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans. Cell 94: 635-645 (1998).




Created by Yuna Kim
Copyright ? 2005 by AG Lab. All rights reserved.
Departmet of Bioscience and Biotechnology
Address : 509 Biomedical Science Research Building Konkuk University
1 Hwayang-dong, Gwangjin-gu, Seoul, Korea



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